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Do you want bigger breasts? Do you think exercise might give them to you? If so, here's a true story that might interest you. (Of course, we asked permission to print this story for you, and the names are changed to protect privacy). A young lady asked me this, regarding exercise and fitness personal training. Her question was "If I train with you, will my breasts get bigger? Will they lift themselves up, become firmer and fuller like they used to be when I was younger? Truthfully, I hesitated momentarily, before answering this one. Yes, I really wanted to motivate her, as well as gain her service as a new fitness client. And, I also wanted to stimulate her existing desire to re-kindle her fire and passion for exercise. My greatest personal satisfaction comes from seeing other people improve themselves, especially when their benefits come from advice, education, suggestions, and/or training techniques that I have brought to them. However, my ethics are much stronger than my desire for profit. Ethics in the diet, exercise, and personal fitness training industry are an extremely valuable commodity. They denote character and intent to provide quality service. Therefore, I smartly hesitated before answering the young lady's question. I could see the look in her eyes. She may have wanted me, as a trainer, to say, "Yes, of course your breasts will become larger, firmer, and fuller, just like they used to be. All you have to do is exercise." The truth, however, is quite surprising and perhaps contrary to your probable expectations. As I began to research the subject, "natural breast enhancement," many truths became obvious, almost instantly. Of course, you find your most immediate replies from Internet sources. Members of the general public, many of whom have no accreditation, formal education, or long-term training expertise, are free to create such highly opinionated responses. Although these individuals (and some small businesses, too) may mean well, they simply lack accuracy, especially in the art and science of conducting skilled research. Now, let me tell you what I noticed right away. Upon my first query on natural breast enhancement, several web sites displayed conflicting information. For example, one site said that herbs, minerals, and vitamins would cause a woman's breasts to enlarge. The next site said that "exercise" would boost breast size by at least one "letter." A third said that "nothing" would help because genetics alone determined breast sizes. A fourth claimed that wearing pressure clamps all day long would increase breasts by at least two cup-sizes. As you might already see, the offerings, replies, and suggestions included various alternatives, methods, and techniques. There were suction and pressure devices, creams, encapsulated hormone products, immune system "enhancers," nutrient supplements, etc. A few sites even boasted about "special secret exercises." (Of course, you had to pay first before they told you what these unique, new "special secret exercises" were, if any.) The exercise science industry says nothing about "special breast enhancement exercises." This type of information is only hype. Don't buy into it. Stick with science. Stick with accredited information sources. Maintain your knowledge through licensed, formally trained professionals. Especially, deal only with specialists who maintain high "ethical" standards. You may be interested to know this. Here is the basic outcome of a comparison between the various natural ingredients associated with "breast health." These ingredients were different from those that claimed to increase "breast size." If you are a candidate for such products, you must be meticulous about the phrasing of such descriptions. There's a saying on the Internet that, "You have to already know what you want, before you can find it." In other words, asking for "breast health" gives you different results than "breast enhancement" or "breast enlargement," or even "natural breasts." For example, properties of nutrients claimed to exert "anti-cancer" functions. Still, others were reportedly claiming to make the breast expand (or, at least "appear" to) swell in size. Certainly, you could rationalize the following. Some nutrients do indeed tend to protect your cells from deterioration. At least, there are some that may offset the formation of cancerous cells. This, however, does not automatically mean that the tissue will appear larger and/or grow bigger. When you refine your "purpose," you are more likely to find something that can provide you with a satisfactory solution. Do You Want the Bottom Line on "Natural" Breast Enlargement? There really is "nothing" available and practical that will give you such results. The only thing that possibly comes close to achieving this for you is the "pressure clamp" concept. That is, you wear pressure clamps all day long for about 20 to 30 days non-stop. Surely, you can see how many people cannot arrange the time for such an activity. Convenience is certainly a factor that affects you. And, can you withstand the discomfort of this type of breast enlargement technique? At least, this idea has some merit, but it's still not your most practical and achievable solution. Now, consider the following. In a "natural" way, nothing exists that will actually make your breasts firmer, fuller, or larger. You can, however, protect the "natural health" of your breasts. Additionally, with exercise, you can naturally increase the size and strength of the MUSCLE layers BENEATH your breasts. These muscle layers (called "pectorals") can give you a slightly more firm appearance. This is true only because the muscles themselves become more firm, NOT your mammary glands. In reality, breasts consist of fat tissue, not muscle. Fat can seldom be "firm" to the touch, and fat is hardly likely to give you a firm, solid appearance. Now, "think outside of the box" for just a moment. Returning to our original story line, the ironic thing is that the woman you read about already possessed very large breasts. Thousands of "decent-sized" ladies would "kill" to have what she already has. However, the feeling that your breasts may not be nice enough also comes from other facts. Your surrounding body parts can also lack THEIR proper shape and symmetry. Your overall fitness (including body fat ratio, flexibility, strength and endurance) may be poor or below average. So, here's a breast enlargement/enhancement/health solution that you can count on, virtually, forever. BECOME TOTALLY FIT. For example, with the woman you read about above, reducing waist size would conversely increase breast size appearance. Do you understand how this works? In exercise science, there is something called a "waist-to-hip" ratio. It measures your cardiovascular risk as well. However, with an excellent waist-to-hip ratio, your body "looks" good, too. In other words, reduce your waistline to enhance your upper body stature, appearance, and appeal. Next, there is your "body composition." This is an approximated measurement of the amount of fat you carry in your subcutaneous tissue layers (immediately below your skin's outer surface). This is a ratio of the fat to muscle your body carries. Via practically any combination of aerobic, bodybuilding, endurance, toning, or strength workout activities, you can remarkably enhance your body composition. This, in turn, enhances the size of your waist, plus the shape of your torso, and consequently, the appearance of your breasts. Therein lies your "breast enlargement," the "natural way." It's time to train your way into a more pleasing appearance, and a higher level of stamina comes with it. It's a win-win situation for you, without medical complications, and with no negative side effects. Help "nature" take its course by helping your body do what it is supposed to do – that is, to PERFORM. Call your trainer or weight management specialist and get more information. Then, step into higher gear with enjoyable and effective diet, exercise, and fitness physical activities. Your breasts will say, "Thank You." pnis enlargement procedure penis enargement surgeon penis enlargment doctor real penis enlargment penis enargement tool pnis enlargement system enlagement erection penis pill vimax penis enhancement secret

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So, you've just put up a profile on some online dating or social networking site. Or maybe you've been online for awhile now, and you think you know the ropes pretty good, right? I'm going to enlighten you on what both sexes have to worry about online and what both sexes have to go thru so you know the truth for once! For one of the online dating guide books I'm writing for guys, I have, for the last 2 ½ years, been on about 35 different dating websites meeting and getting to know women and discovering the true art of online dating or online meeting people. What I have learned about men and women is equivalent to a Ph.D. from Harvard on human behavior, sexuality, and psychology. The biggest things ALL guys have to worry about are women using fake pictures that aren't them and lying about their age online - usually they're older than they say. (Note: The 3 things women lie about the most offline is their real age, weight, and dress size.) The biggest thing women have to worry about guys online is they're married or have a girlfriend, outdated pictures, and of course their own personal safety. (Note: The 3 things guys lie about the most offline is how much they really make, how big their penis is, and how long they can last in bed.) If a guy says he makes $40K, a FedEx driver, says he has an average size thingy, and can last about 15 minutes, he's probably telling you the truth ladies! 1/2 of all single Americans are now or have been online dating. Why you ask? Because the bar, nightclub and dating scene just gets old eventually. Maybe it takes you until you're 25, 30, 35, maybe 40 years old, but it will eventually get old believe me. It's not so much in going out and partying that gets old, but more looking and hoping to meet some hot and great person that you want to date, hook up with, or marry down the road. Having to hear the same drunk meatheads hit on you or grab you. Or for guys look around and see the same unappealing women out and about The intelligent single person of the 21st century also knows it's a numbers game. (I don't mean sleeping around or trying to get a lot of action either for all you players and playettes. Ladies, you have all heard you have to kiss a lot of toads to find your prince, right? Well, online you can kiss hundreds maybe even a thousand times more toads in a tenth of the time you ever could offline. I personally know within minutes of reading most profiles, if any woman has a chance or not with me to go to the next levels. I will explain in greater detail in a few moments. From just talking on the phone or IMing with a woman for an hour or so, I can tell if there is some good chemistry or any kind of anything in the future. I have just honed in on my "Spidey Senses" so much now, and I don't want to waste even a minute of my time or another person's if I don't think anything will ever come of it. This is not rude or mean at all. It's the right and honest thing to do I believe. You're not leading on someone, wasting their time, or setting them up to really get their feelings hurt. Too much of that crap happening already without you contributing to it with all the heartless, selfish, ungiving, and cheating people in the world today and online. What are the 7 stages of online dating and what happens in each stage? Stage 1 In this stage someone winks at you, shows interests in you by posting a comment on your profile, or invites you to their network of friends. Whatever dating site you're on, they all have similar type features. What does this stage mean? Not a whole lot. The person obviously didn't think enough of you or at least not yet to actually take the time and email you. So in our ADD/lazy ass society we just click a button or two to let you know we checked out your profile (Usually that's a lie. They saw your pictures and then on a purely physically based decision they contacted you because of that). Then, we hope the other person sees that we commented or invited them to our network and they make the next move back or take it to the next stage - to email you. Basically the person is trolling the whole ocean looking for a few bites and thinking even a broken watch is right twice a day! Sound familiar? Stage 2 In this stage, someone actually thought enough of your pictures and/or profile to take the time to email you their opinions, curiosity, or interest in you using your dating sites email account. This is the safe, secure way because you're not letting that person into your life at all, and they can only contact you thru that dating site; not your personal email account that you only share with friends, family, business associates, or people you trust at least a little. What does this stage mean? Well, the person took the time out of their day to email you something which is a good thing sometimes and shows their level of interest is now past stage 1. The email could be something crude, lude, sexual, sweet, nice, funny, romantic, flattering, etc. so the jury's out on whether what they send you is a good or bad thing. But unlike a posted comment or invite many people will at least reply back to someone's email that took the time to email them, so if you want to get to know someone I would do this stage for sure. Stage 3 In this stage, mutual cooperation is usually needed because you exchange (or one of you gives the other) you're personal email address. Unless of course the person has their personal email address, which most sites block from showing if you try but some people put their personal email addresses on their site so you can contact directly that way. What does this stage mean? Well, you just let them into your little world a tad bit. Now you can exchange pictures with each other as well as use emoticons and different font styles to get your email message to them more convincingly. That person also, with very little effort, can track down where your internet connection is coming from meaning city/state. It's a good thing to find out to see if someone's lying about where they live or bad if you don't want to give out the city/state of where you live for safety reasons if you're like a porn star, model, or someone in the media and would be prone to get whacko's and stalker types. Keep a look out for Part 2, with further explanations of stages 4-7 about online dating. best pnis enlargement surgery penile enlargment supplement natural penis enlargement technique penis enhancement tool herbal natural penis elargement enlargement manhattan penis free natural penis enlarement penile enlargment product penis enlargement stretcher

While women usually talk about performing a breast enlargement procedure some of the "lucky" ones decide to perform a breast reduction in order to gain some of the lost image and functionality by reshaping their size. In most cases, age deformations, disfigurement caused by accidents, or diseases, are the reasons why women decide to perform a breast reduction cosmetic surgery operation. Determined by her genes as well as by her weight and hormones, the size of a woman's breasts varies with age, height and frame. In fact, while some women develop particularly large breasts from early adolescence, others develop them later in life, during the menopause or following the use of HRT. In many cases, women with large breasts experience a physical and psychological discomfort. Thus, since women can feel very self-conscious and can become depressed about the size of their breasts, many of them resort to the solutions provided through contemporary cosmetic surgery practices like Reduction mammoplasty; generally known as breast reduction. Breast reduction is an operation where the excess fat and skin are removed from the breasts. The breasts are then reshaped to form smaller breasts and the nipples are repositioned. Moreover, breast reduction can also be used to even up the size of the breasts where one is much larger than the other. But since breast reduction is actually a surgery, women tend to get scarred of the results. This is why it is important for the woman that wishes to reduce the size of her breasts to talk with her surgeon and agree beforehand on the desired surgery's outcome. Providing all the past health information to your surgeon is also necessary. The overview of your general health condition can reduce the risks of experiencing any kind of complications during surgery or later after its completion. You will always have a post-operative consultation with your surgeon to review the results and to check on your progress. Once you've returned home, you'll need two to six weeks of rest depending on your age and health. A week or two after surgery, your stitches will either dissolve, or you'll need to return to the hospital to have them removed. Finally, you should consider the results you want to achieve and consult with your experienced breast surgeon before deciding on performing any dramatic change that may have a negative effect to your overall appearance. The surgeon will also give you advice on how best to prepare for the operation. If you are overweight, you may be advised to lose weight beforehand. Since breast size alters with body weight, you will be more suitable for surgery if your weight is stable. Your breasts won't grow again after surgery, but they may still fluctuate in size if you gain or lose weight. Moreover, smokers will be advised to give up because smoking increases the risks of surgery, including delayed healing. Also, in case you are still very young in age, the surgeon will advise you to wait until your breasts have stopped growing before performing the operation. If you decide that you want to have the operation, select a recommended suitably qualified surgeon and ask to sign a consent form. This is to show that you are aware of what the procedure involves, including the possible risks, and give your permission for it to go ahead. Many women find that the benefits of breast reduction far outweigh the side-effects. However, because a breast reduction is done, at least in part, for cosmetic reasons, it is especially important to carefully consider the risks. penis enhancement device pnis enlargement exercise free natural penis enlargment penile enlargment stretcher vimax cheap penis enlargement pills natural pnis enlargement manual penis enargement vimax cheap penis enlargement pills penis enlargement stretcher

The moment was demanding, her looks inviting, and the foreplay electrifying but when the time came to ignite, the spark was missing. Sex, the word itself is enough to quicken pulse and increase blood circulation. It is an incredible experience, fantabulous stress reliever; a good sex provides immense satisfaction, increases intimacy, creates an unending bond. But for many good sex, frequent sex and satisfying sex remains an elusive day dream. Gratifying sex remains a familiar problem for most men around the world and erectile dysfunction is the most widespread cause to blame for failure in bed. In most cases this remains a temporary problem, but in some cases it’s an ongoing problem and ends up hurting a man’s self esteem and breaking his relationship with his partner. The problem becomes more vulnerable with age, its familiar in people aged above forty. Nearly 25% of men face this embarrassing situation at some point in life but it becomes a serious issue if it is rampant. ED is the inability to sustain erection necessary to gratify sexual urge, its not a sexual problem, physical, mental as well as psychological factors contribute to ED, age being the most prominent one. The best part is that it’s treatable at any stage and in all ages. Cialis has been a great contributor in eradicating the problem of erectile dysfunction, and providing millions with the desired sexual pleasure. The FDA approved Cialis hit the market in 1998 along with Viagra and Levitra. • Cialis is safe and gentle ways to re- ignite the desire, the excitement and the sexual response that make sex wonderful and rewarding. •Cialis or Tadafil is phosphodiesterase type 5 inhibitor, while sexual stimulation, it helps the blood vessels in the penis to relax, resulting in flow of blood which causes erection. • Take Cialis 30 minutes to 12 hours before sex and enjoy its 36 hours long-lasting effect, it provides you surplus time to plan and enjoy all your fantasies. • Cialis is available in 5mg, 10mg and 20mg tablets; the maximum recommended dosing frequency is once per day. • The most familiar adverse effects of Cialis include Headache, Myalgia dyspepsia/upset stomach, back pain. • Cialis is strictly restricted for women. • Keep medicine out of the reach of children. penile enlargement before and after enlargment free penile pills sample truth about penis elargement pills manual penis enhancement exercise penis enlagement forum natural penile enlargement exercise best penis enhancement penile enlargment testimonials penis enlargement stretcher

Believe it or not, there is a natural ingredient from Europe that can help change the way your legs feel and the way you feel about the circulation in your legs. Whether we realize it or not, the circulation in our legs can have a huge influence on how we feel and what we do everyday and perhaps even more so every evening. The comfort level of our legs, or better said, their discomfort level at the end of the day can adversely affect our social life and fitness activities - not to mention adversely affecting our sleep. If our legs felt better perhaps we would find it easier to do the things we'd love to do, but find it so difficult to muster the motivation. As if the way our legs can feel at the end of day isn't challenging enough, the changes in the circulation in our legs as we age can seem even more hopeless and discouraging. Now add to that the seeming conspiracy among fashion designers to have us exposing even larger portions of our aging legs and we have a problem that over 80 million Americans with varicose veins understand all too well. (1). Unfortunately, about half of all American women will develop varicose or spider veins at some point in their lives (2). Not only are they unsightly, these leg problems can also cause significant discomfort. Typically, varicose veins are characterized by bulging, blue, sometimes painful and inflamed veins that appear primarily in the calves and thighs. Spider veins, on the other hand, show up as a web of fine lines that can make your legs look like a road map. While age and heredity play a role in the development of varicose and spider veins, weight gain, pregnancy, menopause and the use of hormone replacement therapy can also trigger these vein problems. Making matters worse, chronic inactivity, standing for long periods of time or habitually crossing your legs can make you more prone to injured veins (2). Conventional treatments include surgical stripping, injecting the veins with a chemical irritant or zapping them with lasers. While these approaches can remove existing varicose or spider veins, they will not prevent new ones from developing, since these high-tech treatments do not address the underlying problem of poor circulation. Worse yet, these procedures can also cause infection, scarring, nerve damage and pain (26). If these radical treatments are not an option for you, you'll be happy to hear that there is a natural approach that not only improves the appearance of these ropy, bulging veins, it also fosters leg health to prevent future problems. Veins Explained To understand how varicose veins develop, you need to know a little bit about how blood moves through the body. Essentially, there are two types of major circulatory vessels in the body: the arteries, which channel blood from the heart to the extremities, and the veins, which bring blood from the extremities back to the heart. Of all the veins in your body, leg veins work the hardest to carry blood back to the heart. To accomplish this difficult task, your legs are equipped with specially designed one-way valves that keep the blood moving in the right direction. As efficiently as these valves work, your legs still fight a constant battle against the natural pull of gravity. If the veins can't move the blood efficiently or the one-way valves that prevent the blood from backwashing fail to close properly, blood collects in the legs. This pooling of blood then stretches the vein, causing swelling and injury to the vein's walls (3). Depending on the extent of the enlargement, these veins can show up as either spider or varicose veins. Spider veins are broken capillaries and small veins that appear as jagged red, blue or purple lines on the surface of the skin. While they aren't painful, they can be extremely unattractive. Varicose veins, on the other hand, are thick veins that run deeper beneath the skin. They are far larger and much less attractive than spider veins - and they can make your legs feel fatigued, heavy, achy or even itchy. Varicose veins can also cause burning, throbbing, cramping and restlessness. While these conditions aren't usually dangerous, severe cases can lead to chronic venous insufficiency - a persistent inability of the leg veins to adequately return blood back to the heart (4). Varicose veins are also associated with the development of skin ulcers or a chronic inflammation of a vein - a condition known as phlebitis. Phlebitis is often accompanied by formation of a blood clot, a dangerous situation since the clot can move from the leg vein and travel to the lungs (2). Get a Leg Up with Diosmin Your strategy for battling vein problems naturally is twofold: improving circulation and strengthening the vein walls. The first and simplest measure to improve blood flow is to counteract gravity. Standing or sitting all day makes it harder for blood to move up from the legs and back to the heart. But taking a few minutes to rest with your legs higher than your heart each day allows gravity to help return blood to the heart. Getting in shape can also help relieve varicose and spider veins - and it can even prevent new ones from forming. As we age we lose muscle tone, which adversely affects the health of our legs. Yet adopting a consistent exercise program promotes good circulation and can help to keep our leg muscles, and the blood vessels in our legs, toned. Walking, weight training, low-impact aerobics and swimming strengthen the legs and circulatory system, and help to reduce the throbbing and aching often associated with varicose veins. What you eat can also ease unsightly veins. A low-fat diet filled with fruits, vegetables, beans, legumes and whole grains add key nutrients and fiber to your diet. Eating a fiber-rich diet reduces the chances of constipation which can contribute to varicose veins. Constipation restricts the blood as it returns to the torso through the deep veins in the legs. Straining to have a bowel movement closes off the deep veins in the legs and restricts the flow of blood as it returns to the torso. As the blood backs up, it takes another course through superficial veins, thus the blue streaks in the legs. Eating a fiber-rich diet alleviates and prevents constipation, helping to avoid the damage to the vascular system that can result. In addition to fiber, a diet high in fruits and vegetables also ensures adequate intake of nutrients and phytonutrients, which also help tonify the blood vessels. As a bonus, a healthy diet and exercise program can also jump-start weight loss - an important consideration since carrying too much weight creates extra pressure on your heart and blood vessels, interfering with healthy circulation (2). To strengthen the veins themselves, take a tip from the Europeans. From Austria to France to Italy, women and their doctors have relied on Diosmin for more than 30 years to treat circulatory problems affecting the legs - and with good reason. Diosmin is a unique bioflavonoid derived from citrus fruits and is closely related to other citrus bioflavonoids such as hesperiden, quercetin, and rutin (5). Clinical trials have shown that Diosmin is highly effective in boosting circulation and strengthening the veins in the legs (5). Not only does this improve existing varicose and spider veins, it can also reduce the likelihood of future problems. What makes Diosmin so amazing is its power to specifically target the blood vessels in the legs. Diosmin improves both blood vessel elasticity and microcirculation while relieving pain and inflammation by inhibiting pro-inflammatory prostaglandins and thromboxanes (21,24). Because of its direct action on the integrity of vein walls, Diosmin also reduces the amount of fluid that leaks out of them (21,22). Diosmin's protective benefits do not stop there. Because it is a potent anti-oxidant, Diosmin decreases lipid peroxidation and reduces free radical damage that can undermine vein health (23, 27). In one clinical trial, people who suffered from pain and swelling due to varicose veins experienced significant improvement in their symptoms after taking Diosmin for a few months (6). A review of studies also found that, among more than 5,000 patients with vein disorders, the vast majority not only saw a reduction in their discomfort, they actually saw the swelling in their calves and ankles disappear (7). Across the board, research shows that a daily dose of 500 to 1,000 mg of Diosmin improves the health of leg veins and brings tremendous relief from pain, night cramps and leg heaviness (8,9,10,11). Both short- and long-term use of this highly effective natural ingredient comes without any side effects. It is also so safe that you need not worry about adverse interactions of Diosmin with drugs, foods, lab tests or interactions with diseases or conditions. (5). Help for Hemorrhoids Because Diosmin reduces swelling and bolsters vein health, it can also help people suffering with hemorrhoids - those uncomfortable varicose veins that form in the lower rectum and anus. Along with making it painful to sit, hemorrhoids can itch, bleed or protrude - and almost half of all Americans suffer from them by the time they turn 50 (12). Extensive research conclusively shows that Diosmin can safely alleviate the pain, inflammation and bleeding of hemorrhoids (13,14,15). Best of all, it offers quick relief, often working its magic within a week or two (16). Plus, Diosmin reduces the risk of a relapse (17). Diosmin for Cancer? While no one questions Diosmin's efficacy for treating varicose and spider veins or hemorrhoids, scientists have begun exploring other ways this potent flavonoid may boost health. Their main focus - cancer prevention - especially oral and skin cancers. Researchers haven't conclusively identified the cancer-fighting component in Diosmin, but preliminary experiments show that this flavonoid inhibits the proliferation of cancer cells (18). In two studies pitting Diosmin against other flavonoids like rutin, grapeseed extract and red wine, Spanish investigators found that Diosmin was considerably more effective at reducing the number of metastatic melanoma cells (a potentially deadly type of skin cancer cells that spread through the body) than any of the other flavonoids tested (19,20). Other studies have found that Diosmin puts the brakes on the spread of cancer cells in the mouth (25). Although it could be years before science conclusively proves Diosmin's cancer benefit, this nutrient can't be beat for supporting vein health. Along with taking supplemental Diosmin, there are several simple strategies you can employ to encourage healthy circulation. Eating a high-fiber, anti-oxidant rich diet and getting plenty of exercise can help keep veins in top form. And remember to take a break and put your feet up every now and again. References: 1. American Society for Dermatoloic Surgery. 2. National Women's Health Information Center. U.S. Department of Health & Human Services. 3. American College of Phlebology. 4. Society for Vascular Surgery. 5. Diosmin Monograph. Alternative Medicine Review. 2004;9(3):308-311. 6. Ting AC, et al. Clinical and hemodynamic outcomes in patients with chronic venous insufficiency after oral micronized flavonoids therapy. Vascular Surgery. 2001;35(6):443-447. 7. Ramelet AA. Daflon 500 mg: symptoms and edema clinical update. Angiology. 2005;56 Suppl 1:S25-S32. 8. Bergan JJ. Chronic venous insufficiency and the therapeutic effects of Daflon 500 mg. Angiology. 2005; 56 Suppl 1:S21-S24. 9. Nicolaides AN. From symptoms to leg edema: efficacy of Daflon 500 mg. Angiology. 2003;54 Suppl 1:S33-S44. 10. Smith PC. Daflon 500 mg and venous leg ulcer: new results from a meta-analysis. Angiology. 2005; 56 Suppl 1:S33-S39. 11. Jantet G. Chronic venous insufficiency: worldwide results of the RELIEF study. Reflux assessment and quality of life improvement with micronized Flavonoids. Angiology. 2002;533:245-256. 12. National Institutes of Health. 13. Lyseng-Williamson KA, et al. Micronised purified flavonoids fraction: a review of its use in chronic venous insufficiency, venous ulcers and haemorrhoids. Drugs. 2003;63(1):71-100. 14. Meshikhes AW. Daflon for haemorrhoids: a prospective, multi-centre observational study. Surgeon. 2004;2(6):335-338. 15. Kecmanovic D, et al. PHLEBODIA (diosmine): a role in the management of bleeding nonprolapsed hemorrhoids). Acta Chirurgica Iugoslavica. 2005;52(1):115-116. 16. Diana G, et al. Activity of purified diosmin in the treatment of hemorrhoids. La Clinica Terapeutica. 2000;151(5):341-344. 17. Misra MC, et al. Randomized clinical trial of micronized flavonoids in the early control of bleeding from acute internal haemorrhoids. British Journal of Surgery. 2000;87(12):1732-1733. 18. Browning AM, et al. Flavonoid glycosides inhibit oral cancer cell proliferation - role of cellular uptake and hydrolysis to the aglycones. Journal of Pharmacy and Pharmacology. 2005;57(8):1037-1042. 19. Martinez C, et al. Treatment of metastatic melanoma B16F10 by the flavonoids tangeretin, rutin, and diosmin. Journal of Agricultural and Food Chemistry. 2005;53(17):6791-6797. 20. Martinez C, et al. The effect of the flavonoids dioxmin, grapeseed extract and red wine on the pulmonary metastatic B16F10 melanoma. Histology and Histopathology. 2005;20(4):1121-1129. 21. Ramelet AA. Clinical benefits of Daflon 500 mg in the most severe stages of chronic venous insufficiency. Angiology. 2001;52 Suppl 1:S49-56. 22. Cyrino FZ, et al. Micronization enhances the protective effect of purified flavonoidsfraction against postischaemic microvascular injury in the hamster cheek pouch. Clinical and Experimental Pharmacology & Physiology. 2004;31(3):159-162. 23. Bergan JJ, et al. Therapeutic approach to chronic venous insufficiency and its complications: place of Daflon 500 mg. Angiology. 2001;52 Suppl 1:S43-7. 24. Katsenis K. Micronized purified flavonoids fraction (MPFF): a review of its pharmacological effects, therapeutic efficacy and benefits in the management of chronic venous insufficiency. Current Vascular Pharamcology. 2005;3(1):1-9. 25. Browning AM, et al. Flavonoid glycosides inhibit oral cancer cell proliferation - role of cellular uptake and hydrolysis to the aglycones. Journal of Pharmacy and Pharmacology. 2005;57(8):1037-1042. 26. National Women's Health Information Center. U.S. Department of Health and Human Services, Office on Women's Health. 27. Villa P, et al. Protective effect of diosmetin on in vitro cell membrane damage and oxidative stress in cultured rat hepatocytes. Toxicology. 1992;73:179-189.