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Medical hair restoration in the literal sense includes the hair loss treatment which depends upon the use of medicines. Unusual hair loss both in men and women is caused by the alterations in the androgen metabolism. Androgen is a male hormone which has a major role to play in regulation of hair growth or hair loss. The dermal papilla is the most important structure in a hair follicle which is responsible for hair-growth. It is the dermal papilla, the cell of which divides and differentiates to give rise to a new hair follicle. The dermal papilla is in direct contact with blood capillaries in the skin to derive the nutrients for the growing hair follicle. Research has shown that dermal papilla got many receptors for androgens and there are studies which have confirmed that males have more androgenic receptors in dermal papilla of their follicles as compared to females. The metabolism of androgen involves an enzyme called 5 alpha reductase which combines with the hormone androgen(testosterone) to form the DHT (Dihydro-testosterone). DHT is a natural metabolite of our body which is the root cause of hair loss. Proper nutrition is critical for the maintenance of the hair. When DHT gets into the hair follicles and roots (dermal papilla), it prevents necessary proteins, vitamins and minerals from providing nourishment needed to sustain life in the hairs of those follicles. Consequently, hair follicles are reproduced at a much slower rate. This shortens their growing stage (anagen phase) and or lengthens their resting stage (telogen phase) of the follicle. DHT also causes hair follicle to shrink and get progressively smaller and finer. This process is known as miniaturization and causes the hair to ultimately fall. DHT is responsible for 95% of hair loss. Some individuals both men and women are genetically pre-disposed to produce more DHT than the normal individuals. DHT also creates a wax-like substance around the hair roots. It is this accumulation of DHT inside the hair follicles and roots which is one of the primary causes of male and female pattern hair loss. Blocking the synthesis of DHT at molecular level forms the basis for the treatment of MPHL ( male pattern hair loss) and FPHL female pattern hair loss). There are many natural DHT blockers and a number of drugs which are used for medical hair restoration. Let us see the main drugs which are available for medical hair restoration in men and women. Minoxidil Minoxidil has the distinction of the first drug being used for promoting the hair restoration. This medical hair restoration treatment drug was used earlier as an oral antihypertensive drug, but after its hypertrichosis (excessive body hair) effects were noticed, a topical solution of the drug was tested for its hair growing potential. Minoxidil was then approved as medical hair restoration treatment drug for men by the US Food and Drug Administration (FDA) in 1988 as a 2% solution, followed by 5% solution in 1997. For women, the 2% solution was approved in 1991. Though 5% solution is not approved for women, it is used as a medical hair restoration treatment by many dermatologists worldwide. Both solutions are available without a prescription in the US. Mechanism of action Minoxidil is thought to have a direct mitogenic effect on epidermal cells, as has been observed both in vitro in vivo. Though the mechanism of its action for causing cell proliferation is not very clear, minoxidil is thought to prevent intracellular calcium entry. Calcium normally enhances epidermal growth factors to inhibit hair growth, and Minoxidil by getting converted to minoxidil sulfate acts as a potassium channel agonist and enhances potassium ion permeability to prevent calcium ions from entering into cells. Thought the exact action of minoxidil preventing the formation of DHT has not been shown but the drug has been shown to have a stabilizing effect on the hair loss. The result of the drug takes about few months time to be evident since it is the time which is necessary for restoring the normal growth cycle of hair fibers. Use of Minoxidil has approved by FDA for men (Norwood II-V) and women (Ludwig I-II ) older than 18 years. It is used as a medical hair restoration treatment either for frontal or vertex scalp thinning. It brings about an increase in density which is mostly caused by conversion of miniaturized hairs into terminal hairs rather than a stimulated de novo re-growth. The hair loss becomes stabilized after continued use of drug, which takes about a year’s time for the medical hair restoration treatment to show its complete results. Hair loss restoration treatment with 0.05% betamethasone dipropionate and 5% topical minoxidil are found to be superior to minoxidil alone. Topical minoxidil is very well tolerated and adverse effects are mainly dermatologic. The most frequent adverse effect is an irritant contact dermatitis. Though minnoxidil does not have any effect on blood pressure, it should be used with caution in patient with cardiovascular diseases. It is also contraindicated in pregnant and nursing mothers. Finasteride The drug finasteride was earlier used as treatment for prostate enlargement, under the medical name Proscar. But in 1998, it was approved by FDA for the Medical hair loss restoration in MPHL. Mechanism of Action Medical hair restoration treatments with Finasteride depends upon its specific action as an inhibitor of type II 5α-reductase, the intracellular enzyme that converts male hormone androgen into DHT (Dihydro Testosterone). Its action results in significant decrease in serum and tissue DHT levels in even in concentration as low as 0.2mg. Finnasteride is able to stabilize hair loss in 80% of patient with Vertex hair loss and in 70% of patients with frontal hair loss. Most of these patients are able to grow more hair or retain the ones they have. The peculiar thing about Propecia is that its effect is more pronounced in crown area than in the front. The hair that grow after the medical hair restoration treatments are better in texture and are thicker, more like the terminal hair. The best thing about medical hair restoration treatment with the finnasteride is that it is well tolerated and has minimal side effects. Sexual dysfunction (decreased sex drive, erectile dysfunction, and decreased semen volume) are observed in about 3.8% of cases. But these side-effects subside within few months of Medical hair restoration treatments or disappear within a week’s time as soon as the treatment is stopped. It generally requires about 6 to 12 months for the m edical hair restoration treatment to be apparent but the side effects appear earlier. So even after the medicine is stopped, there is no possibility of loosing the hair that has been gained, but the side effects are sure to disappear. Many hair restoration surgeons find Propecia (finasteride) to act as an excellent adjunct to the surgical hair restoration. There are several benefits of this kind of combination therapy. As the Medical hair restoration with Propecia brings about a hair re-growth in the crown area, it has a complementary action; it allows the surgeon to have more donor hair to be available for frontal hair transplant and design the hairline at his own will. Since finasteride has no effect in the frontal area of the scalp, it does not have any interference with the surgical hair restoration. Combination Therapy There are reports which say that use of finasteride and topical minoxidil combination therapy as a Medical hair restoration treatment is of more advantage in cases of mild to moderate MPHL. Further studies are in progress. Many hair restoration doctors have already started the use of combination therapy in order to obtain better hair growth. Anti Androgen Therapy For women with hyperandrogonism( with increased levels of androgen) who do not respond well to minoxidil, antiandrogen therapy is another option of Medical hair restoration. In UK the most commonly used anti-androgen for women is CPA (cyproterone acetate), which is used in combination with ethinyl-estradiol. However, in United States, where CPA is not available, the aldosterone antagonist spironolactone is the alternative choice of hair restoration doctors. Flutamide Medical hair restoration with flutamide has shown improvement as hair loss restoration treatment in women with hirsutism. For hyperandrogenic premenopausal women, flutamide is a better medical hair restoration agent than both the CPA or finestride. Hair loss restoration management is a structured process which depends upon many factors along with the medical hair restoration. 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Peyronie's Disease: Peyronie's Disease (pay-row-KNEES) is acquired in adult life rather than at birth (like hypospadias). Men with Peyronie's disease usually seek medical attention because of painful erections and difficulty with intercourse. Peyronie's Disease is caused by the formation of hard plaque on the upper or lower side of the penis. The plaque forms in layers containing erectile tissue. The local inflammation eventually develops into a full scar. This scar tissue is hard and inflexible, and causes the penis to bend when erect. The effects of this bend are far less noticeable when the penis is in a flaccid state. François de la Peyronie, a French surgeon first described Peyronie's disease in 1743. Early writers classified it as a form of impotence, now called erectile dysfunction (ED). Peyronie's disease can be associated with ED; however, experts now recognize ED as only one factor associated with the disease, a factor that is not always present. This affliction leaves the penis bent distinctly in some direction. Often, the angle is in excess of 45 degrees and results in serious pain during erection and the impossibility of normal sexual intercourse. Bear in mind that a gentle curve in the penis is natural and you probably don’t have Peyronie's Disease! There is no need to worry about a curved penis unless the curve suddenly appeared and/or you're penis has experienced some sort of trauma. Unfortunately, symptoms of the disease may develop methodically or overnight. Overnight appearances are usually due to some sort of serious penile trauma, but not always. If you think that you have Peyronie's Disease, then I highly recommend you see your healthcare provider, who may refer you to an urologist. Hypospadias: Hypospadias is a congenital disorder of the penis, an abnormality that may affect up to one out of every 400 to 500 male infants. Instead of having a urethral opening at the end of the penis, boys born with hypospadias have an opening on the underside of the shaft of their penis. If this causes a problem with urination, the condition can be surgically corrected. About 10% of boys born with this defect may also have undescended testicles. Surgery is most often performed before the child reaches school age. The surgery involves creating a tube to extend the urethra to the end of the penis. The original hole is most often left as it is since the urethra now bypasses it. Although the penis has two holes, only one is functional. Otherwise it should be a normal functioning penis. Priapism: Priapism is an involuntary prolonged or painful erection that can persist for hours, days and is not associated with sexual arousal. It can occur at any age and is a true emergency with risks of subsequent impotency. Primary priapism is the result of trauma or infection. Secondary causes include sickle cell disease, spinal cord injury and stroke. Various medications can also contribute to this condition. Phimosis: Phimosis refers to a tightening of the skin of the foreskin that prevents retraction over the glans—the sensitive erectile tip of the penis. There are two typical forms of this tightness: an infant phimosis and the phimotic ring or band. An infant phimosis has an easily recognizable tubular form, this is common and healthy in infants but occasionally will continue into adulthood. The adult phimosis is a thin contour of skin tissue located towards the front of the inner foreskin and it narrows the opening of the foreskin. A phimotic ring can make retraction of the foreskin over and behind the glans impossible, painful, or difficult, the foreskin may even get stuck behind the glans. This condition is often treated by circumcision, however, there are less invasive procedures depending upon the degree of phimosis, see several urologists for opinions if you have this condition. For “simple” phimosis, stretching of the foreskin may be a method for treatment that may work. Steroids and surgery are other options. For more on this condition do a search on google. Large Penis Veins: It’s normal for men to have prominent veins on their penis. For some men, sometimes the appearance of veins is a result of poorly functioning valves in their testicles. If you see your veins changing in size or color, it’s time to see your friendly urologist. best penile enlargement surgery do penis enlarement pills work penile enlargment result penis enargement pills product real penis enlarement pnis enlargement review enlargement manhattan penis natural penile enlargement and lengthening penis elargement herb

There are various types of birth control available to couples wanting to avoid pregnancy. Of all of these methods only condoms offer a high degree of protection against infection by HIV and other STDs (Sexually Transmitted Diseases) at the same time as providing highly effective prevention of unwanted pregnancy. But just how effective are condoms at preventing pregnancy, and what are some of the factors that have a bearing on their effectivenesss? Effectiveness of Condoms in Preventing Unintended or Unwanted Pregnancy When determining condom effectiveness, it is important to recognize that, as with all methods of contraception, the effectivness of condoms decreases when they are not used correctly. According to one large study, "In one year, only two of every 100 couples who use condoms consistently and correctly will experience an unintended pregnancy - two pregnancies arising from an estimated 8,300 acts of sexual intercourse, for a 0.02 percent per-condom pregnancy rate." Other studies that do not measure for incorrect use, but only for "regular use", indicate that the pregnancy rate may be as high as 15% of couples. But this number is skewed because it includes improper use. The main reason that condoms sometimes fail to prevent pregnancy is incorrect or inconsistent use, not the failure of the condom itself. These studies just ask women how often they have become pregnant when their partners use condoms. But the "failure rate" derived from these statistics includes cases of incorrect usage, tearing due to mishandling of the condom or rough sexual practices, or even where the couple did not use a condom every time they had sex. So it is worth repeating. When condoms are used consistently and correctly they have a very high prevention rate -- between 97% and 99%. But they must be used "consistently and correctly" in order to be this effective. Ways to Prevent Condom "Failure" Here is what you must do to insure you are getting the best protection possible from condoms: Use a condom every time you have sex. The condom must be applied as soon as erection occurs and before any sexual contact (vaginal, anal or oral). Be sure not to tear the condom with teeth or fingernails. Do not use oil-based lubricants such as petroleum jelly (vaseline), cold cream, hand lotion or baby oil, since it can weaken the latex. Withdraw from the partner immediately after ejaculation, holding the condom firmly to keep it from slipping off. Some other Condom Considerations When you buy condoms, read the label. Tests have shown that latex condoms are more likely to give you the added side benefit of preventing the passage of STDs. High quality condoms will be in a package that says the condoms are effective in preventing disease. If the package doesn't say anything about preventing disease, the condoms may not provide the protection you want, even though they may be the most expensive ones you can buy. Novelty condoms (flavored, textured, etc.) are intended primarily for sexual stimulation, not protection. Again, read the label. If it does not say anything about either disease prevention or pregnancy prevention on the package, then it will not be as effective a barrier against pregnancy and disease. For proper protection, a condom must unroll to cover the entire penis. Condoms which do not cover the entire penis will not give you maximum protection. This is another good reason to read the label carefully. Female condoms, while reasonably effective, are not quite as good as male condoms. Although using spermicide by itself (without a condom) is not a very effective way to prevent pregnancy, using condoms that have spermicide added increases their effectiveness. Condoms available from vending machines are not always of top quality. Look for brand names, and read the label carefully. Bright sunlight and heat can weaken the latex, so store them away from sunlight and in a cool place. Where should I buy condoms? If you are buying online, make sure the online store carries a broad range of name brand condoms, contains helpful information about condoms, and is reachable by phone so you can talk to a real person. The best advice is to buy from an established source that deals only in name brand products. natural penis elargement exercise vimax forum manual penile enlargement penile enlargment surgery cost buy penis enlargment pills free penis elargement exercise penis enlargment system free penis enlagement penis elargement herb

Rosacea is a chronic, lifelong skin condition that affects (most often) the face. The disease is common: approximately 1 in every 20 Americans has rosacea. Women are affected more often in the early stages (flushing and erythrosis), but more men progress to the advanced stages and rhinophyma is seen almost exclusively in men over 40 years of age. Rosacea is characterized by various skin disorders and sufferers must contend with skin flushing, erythrosis (reddish or purplish discoloration of the skin), teleangiectasia (permanent enlargement of small blood vessels), papulopustular rosacea (papules are small, red, raised bumps; pustules are similar but they contain pus) or rhinophyma (enlarged, red, swollen nose) and for many people, some of these signs and symptoms are very common; approximately 94% of people with rosacea have flushing. These attacks last from a few minutes to several hours, and the flushing seen in rosacea is intermittent in nature. The disease, to a greater or lesser degree, is progressive, and the more pronounced skin lesions will usually follow sporadic episodes of flushing. The exact cause of rosacea has not been determined, but here are many theories. Exposure to the sun may be one factor, and exposure to the sun can precipitate acute episodes of flushing. Another possible cause are skin mites, Demodex folliculorum and Demodex brevis. These tiny insects usually live at the base of hair follicles. They are often found on the faces of people with rosacea, and it has been suggested that they may initiate an inflammatory reaction (Inflammation dilates blood vessels and this contributes to the flush, and it may also damage the blood vessels, causing them to be permanently dilated). Infection with the common bacteria, Helicobacter pylori, has also been suggested as a cause. There may also be genetic defects in the vasculature of the skin that causes hem to become easily - and permanently - dilated. The signs and symptoms of rosacea are not dangerous, but they can be uncomfortable, unsightly, and disfiguring. (However, rosacea can affect the eyes. Approximately 3% to 58% of patients with skin changes will have eye problems and rosacea keratitis can lead to blindness). Yet although there is no cure for rosacea, the disease can be managed. Topical medication, oral medications and laser therapy can all be used to control flushing and to remove some of the skin blemishes, swollen blood vessels and discoloration. However, it would be far more preferable to prevent outbreaks of flushing and the development of erythrosis and papulopustular lesions. It is well known that there are certain factors - sunlight, stress, heat - that can trigger rosacea signs and symptoms, and food has been identified as a trigger. What foods have been implicated as causes of rosacea signs and symptoms? The list is long, and there is obviously individual variations in susceptibility: high doses of B6 and B12, chocolate, tomatoes, hot beverages, hot sausage, red pepper, black pepper, vinegar, paprika, white pepper, garlic, wine, hard liquor, beer, cheese, yogurt, sour cream, milk, citrus fruits, eggplants, avocadoes, spinach, raisins, figs, bananas, and marinated meat. Why do these foods exacerbate rosacea? No one knows for sure, and given the fact that the exact cause of rosacea hasn't been clearly determined, that's not surprising. However a look at the pathophysiology of rosacea may provide some clues. The flush that is so common in people with roseacea is caused by dilation of the small blood vessels of the face. Why this occurs is not certain. The blood vessels may be genetically weak, or they may be damaged by years of exposure to the sun. There may also be an increase in the number of blood vessels, or there may be damage to the walls of the blood vessels. Whatever the cause, the blood vessels (which in the face are very close to the surface) dilate. Many of the foods that trigger flushing attacks most likely do so by increasing body temperature, and in order to lose body heat, blood vessels dilate. Others may cause flushing by stimulating the release of histamine. This is a naturally occurring substance that dilates blood vessels and some foods, e.g. beer and citrus fruits may stimulate the release of histamine. penis enlarement tip does penis enlagement work prosolution pnis enlargement pills vimax medical penis enlargement do penis enlarement pills work truth about penis enlarement natural penis enlarement exercise natural penis elargement exercise penis elargement herb

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