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Viagra (Sildenafil citrate), which millions of men take for erectile dysfunction (ED), reduces the effects of hormonal stress on the heart by half, according to a study published online in the journal Circulation.
Viagra causes genital blood vessels to expand, which helps in maintaining an erection. Recent research also has pointed to its potential usefulness in treating pulmonary hypertension. Prior to the latest findings by a team of Johns Hopkins researchers, it was thought to have little effect on the heart.
Viagra, or sildenafil, blunts the strengthened heart beat caused by chemically induced stress, according to study senior author and cardiologist David Kass, MD, a professor at the Johns Hopkins University School of Medicine and its Heart Institute. It thereby lessens both the excess amount of blood and the force used to pump it to the body.
"Sildenafil effectively puts a 'brake' on chemical stimulation of the heart," says Kass.
Prevents and Reverses Effects of High BP
These findings are believed to be the first confirmation in humans that Viagra has a direct effect on the heart. In earlier research, Kass and his team observed a similar effect in mice; Sildenafil blocked the short-term effects of hormonal stress in the heart.
Related studies by the group show that sildenafil also prevents and reverses the long-term effects of chronic high blood pressure on the heart.
Sildenafil reversed the negative effects on heart muscle weakened by heart failure and enlargement -- a condition called hypertrophy -- in mouse experiments Kass and his team carried out earlier this year. They reported their results in the journal Nature Medicine.
"But we had no firm evidence as to whether or how this therapy might work in the human heart," says Kass. "Our latest research provides firm evidence this drug does indeed have an important impact on the heart."
Increased Heartbeat Was Slowed
Thirty-five healthy men and women, with an average age of 30 and no previous signs of coronary artery disease, participated in the six-month Johns Hopkins study. Within a three-hour timeframe, each participant received two separate injections of dobutamine (5 micrograms per kilogram for five minutes), a synthetic, adrenaline-like chemical that increases heart rate and pumping strength.
Between injections, study participants were assigned randomly to a group that was treated with sildenafil (100 milligrams taken orally) or to a group given a sugar pill placebo. All participants then were given the second dobutamine injection to see what effects sildenafil or placebo had on the heart.
Measurements of heart function were made before and after each injection. These included blood pressure readings, electrocardiograms and echocardiograms. Blood samples confirmed relatively equal levels of sildenafil and other enzymes.
Each dobutamine injection stimulated heart function, increasing heart rate and the force of each heartbeat used to pump blood throughout the body, results showed.
"This stimulation is similar to the way the nervous system normally increases heart function when triggered by emotional or exercise stress, or in diseases such as heart failure," notes Kass.
After the first injection of dobutamine, the force of heart contraction increased by 150 percent in both groups. In the placebo group, this increase repeated itself after the second injection. However, in the group treated with sildenafil, the increased heartbeat was slowed by 50 percent, resulting in a smaller increase in blood flow and blood pressure generated by the heart in response to chemical stimulation.
Between injections, heart function was not altered in the sildenafil group, demonstrating the absence of adverse side effects on the resting human heart.
Stops PDE5A Action
"Knowing more about the effects of sildenafil on heart function will allow for safer evaluation of its use as a treatment for heart problems," says Kass.
"Our results set the stage for further studies of sildenafil's immediate and long-term effects on the heart and its ability to modify other neurohormonal and stress stimuli, including adrenaline and hypertension," he adds.
While the precise biological actions of sildenafil in the heart are not fully understood, the drug is known to work by stopping the action of an enzyme, called phosphodiesterase 5 (PDE5A), Kass explains. This enzyme is involved in the breakdown of a key molecule, cyclic GMP, which helps control stresses and limit overgrowth in the heart.
PDE5A is also the biological pathway that sildenafil blocks in the penis to prevent the relaxation of blood vessels and thus maintain erections.
Copyright 2005 Daily News Central
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“How Body Image Affects Sex”
A person’s body image affects his or her entire life. Body image can affect a person’s outlook, their career, their relationships with others, and especially their sex life.
A person who has a poor body image will perceive him or herself as unattractive to other people. This unhealthy mental outlook will start to influence their personality and behavior to the point of projecting negative feelings.
This is a shame because people who have a good body image, who see themselves as attractive to others, usually are happier. They tend to advance in their career. They enjoy more productive relationships. And yes, they have more sex. (And better sex)
Body image has little to do with physical attributes, and more to do with self-confidence. People who have a poor body image might actually be physically attractive to others, while people who are just average looking may have a good body image and be exceptionally appealing to others.
Body Image Is Powerful
Due to many different factors, including upbringing and the modern media’s distortion of sex appeal, a man or a woman may develop a very poor body image and become outright embarrassed about their physical appearance. This can cause a person so much stress and worry, that they simply withdraw socially. They do not date or try to meet new people and so end up sexually starving themselves.
Whereas body image is known to affect more women than men (over 70% of women polled stated they were not happy with their bodies, compared to 33% of men), men also can develop a poor body image; whether late in life after physical changes take place or starting from puberty and on into adulthood. Common body areas in men that are brought into question when a poor body image develops are skin, hair, nose, body shape, eyes, penis size, chest and stomach.
Some of these worries could be media influenced just as it is in women. Top male movie stars, porn stars—or worse yet computer-generated action heroes?—may have perfect bodies and set too high a standard to reach. On the other hand, psychological problems, a hard upbringing, or any recent traumatic experiences could also account for a poor body image.
The Truth About Your Body
Are you happy with your body? Are you proud of who you are and do you feel sexy whenever you dress for the occasion? If your first reaction is no!, or just an uncomfortable cringe, then maybe you have a poor body image. If that’s the case, then we have good news and better news for you.
First the good news. Poor body image is just a condition of the mind. While most people who suffer from low self-esteem are worrying about their physical appearance, other people are noticing the features they do like. If a man doesn’t have a perfect waistline, then many women will find beauty in his eyes, his smile or sense of humor. Just because a woman frets over her voluptuous figure doesn’t mean many men don’t find her curves quite sexy. Ironically, in many relationships the one physical flaw a person thinks he or she has can be charming to the partner.
Looks aren’t everything. And for the most part, people actually look good. But remember that whatever you are feeling inside is what you will project. So don’t spell out with your body language that you’re unattractive and unlovable. Sexiness, attractiveness and an appealing presence is determined by your own level of confidence and understanding, not your physical imperfections. (Which by the way, everybody has. Even movie stars, off camera)
Now the better news. The better news is that if think you have a very poor body image (meaning you think you’re ugly in some way) and are afraid to start dating because of the way you look, then sex surrogacy can help you!
How Sex Surrogacy Can Help
Sex therapists and sex surrogates can help men or women with body image problems. They can restore a person’s confidence. They can teach clients the fundamentals of dating, and better yet, the importance of loving themselves. Anyone can be told “to love himself”; but few educators can teach another person how to go about doing this, how to put away their fears and come to a healthy readjustment of their attitude. Sex surrogacy can do this. Sex surrogates can teach you how to perceive your body image in a kind and gentle way. This education can be done in many ways including talking concerns through with a therapist, receiving reassurance and comfort, engaging in emotional and mental exercises, and learning physical and sexual touching. Surrogate therapy has proven successful for many people who were once lonely, but who are now enjoying a better life and healthy outlook on life. (And yeah, better sex)
Thousands of people every year would rather have cosmetic surgery done than simply come to a better understanding of themselves, their bodies and what society expects of them. There’s hope for you too and it’s not by going under the knife. If you have low self-esteem or a poor body image, then running away from social activity (or from all of society and reappearing with a brand new face) is not the answer.
Improving your body image is. And seeking solutions through sex surrogacy may be just what you need.
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Oh, the little soldier won't stand to attention. The little soldier does not want to play. Now I am not talking about a toy. I am talking about erection. The soldier is sometimes a little shy. As we grow older into adult men, many of us will experience erection difficulty at one time or another. And also for some of us men, this may be a on going problem. At this point, you should be seeking some kind of treatment.
So how would you know if you have a problem with your little soldier? If you are just finding out that you are having difficulty in keeping or even having a erection, well then yeah, this is a strong indication here. These erection problems are known as erectile dysfunction or impotence. This is a man's inability to have satisfaction in erections for sexual intercourse.
Also, the men who are experiencing this form of erection problem is commonly at the age of 60. And what I am telling you is that aging is a factor in erectile dysfunction. This is associated with the decrease in male hormones.
What a man should do is start having physical examinations. This is the first step in the treatment process. This should be done so you can rule out injury, diseases, and disorders: Diabetes, high cholesterol, kidney disease, alcoholism, multiple sclerosis or even high blood pressure. Go to the doctor and check to see if any of these health problems are going on. The doctor will develop your history as a patient and then will discuss treatment with you. Some treatments like vacuum devices might be prescribe. Viagra, Levitra or Cialis may be prescribe to you as well.
Now listen to me, don't even let it get this far. Intervene Now!! Take care of your prostate. Keeping the blood flowing regularly through your penis will produce better erections. The male erection. Very important to stay healthy. More resources and details on a mans health is available at my blog. Looking forward to blogging with you again soon.
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Male to Female Breast Transformation - The Natural Way..
There are now natural options for men wanting to grow breasts that look, feel and contour just like that of a woman. The amount of growth depends on the supplement or method chosen for augmentation, the amount of time on the chosen product or system, and some other lifestyle factors such as diet, massage and exercise that can help lead the way to successful enlargement of the male breast.
The natural phenomena of male breast enlargement is called gynecomastia, an often unwanted side effect caused by imbalances in hormones, and excess weight.
For men who desire to grow female-like breasts, the options are almost identical to a women's options for nonsurgical augmentation. While men can also undergo surgical breast augmentation, it may be more difficult due to a lack of protruding flesh to work with, since most men do not have a lot of extra tissue in the chest area to be conducive to implant insertion. Because of this, male breast augmentation surgeries can often come out looking more un-natural than usual, due to a lack of fleshy tissue to cover the round, and sometimes hard looking implant.
This is precisely why men, whether they be transgender or simply have a fetish desire to grow breasts, are looking for better and more effective and natural looking options to enlarge their chest. There are countless success stories from men who have tried natural breast enhancement products, just like women, and experienced excellent results with adequate length of time on the product, as well as proper and consistent usage.
Biological male breast tissue does not behave all that differently from female breast tissue. When exposed to the right amount of external stimulation factors, as well as the right formula for hormonal and glandular stimulation, the environment for additional breast growth is created.
How Can A Man Achieve Successful Breast Growth?
Men are subject to the same guidelines as women too in most cases, and for most male breast enhancement products the same guidelines apply. It is advisable to combine breast massage as a stimulating factor to set the stage for maximum "breast expansion" while adhering to a natural enhancement routine.
This is most effective when the massage is done with a quality serum or cream formulated with external stimulating factors, such as caffeine (although caffeine should not be orally taken while on a supplement - it will dilute the effectiveness of the product usually), and other stimulating ingredients containing plant estrogens and firming and toning tonics.
Some lighter chest exercises will help to lift the pectoral muscles so that the breast tissue that is currently there and any subsequent breast growth from supplementation is forced outward. This also helps to round, tone and firm the breast area for a fuller look that is more feminine and curvaceous. This may include some lightweight chest flies, modified push ups, light squeezing of the lateral pectoral muscles, or the muscles that run up the side of the breast.
A balanced diet is always recommended for men on breast supplements. A balanced diet creates an ideal environment that is more conducive to breast growth by regulating the hormones and allowing a supplement to better perform its duties.
Men wanting to grow breasts have some excellent options. The effectiveness of natural supplementation has been proven through personal testimonials and even pictures have been documented proving its effectiveness on biological males. So if you are a male looking to enhance your current breast size and further feminize your body, there are options out there - you just need to pick the right product or regimen for you.
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I remember when I was in eighth grade in school years ago and listening to Pink Floyd. I heard a song way back then that became a favourite of mine at the time and still is today. It was called Comfortably numb. At the time of listening to it back then, I thought it was all about heroin abuse.
A year or so later I heard another song by an Australian band called the Choirboys that had lyrics that said: “You don’t need anyone, no you don’t need anyone; when you run the paradise.” Once again I saw this as the paradise that is found by the injection of heroin.
In the movie Pulp Fiction, just a few years ago, I saw the absolutely mind blowing rush one can get from the injection of a needle, and how heroin really is like the big daddy of them all. For even the name itself boasts of its awesome ability and power and how it should be worshipped. We all know about branding and the power of a brand name, if it’s used properly. Just think of Coke, Mc Donald’s, and Disney and suddenly you have an emotion and hopefully a positive emotion come to mind. The word heroin is no mistake. It’s available when you need the ultimate peace and numbness, and you put the father of all drugs into your arm like a doctor gives medicine, you go and put the Hero in.
I am fortunate in one way. I am sure it was an act of God and nothing short of it. As I was growing up, our house was a halfway house for recovering heroin addicts. They came around to our house on rainy Sundays for lunch and when they were healed often stayed with our family until they could find a permanent place of accommodation. They came to us raw and fresh out of rehabilitation. It was their words, and their tears that showed me heroin had its costs on a personal life and wasn’t just the hero in these guy’s life, but their master for many years. They who worshipped the drug and fought, begged borrowed and stole to inject it, were broken individuals who readily cried and told of the horror the drug demanded of them.
Yes, heroin is a powerful drug and I’ll admit that it will make you leave this world we are in, and you will float and kick back into a comfortable numbness. Yes. You won’t need anyone when you run to paradise. But it comes with a price.
I thank God I saw the pain in the drug and never injected it myself. Oh boy I came close and yes I mixed in all the right circles, but I never succumbed to its tantalizing beckoning. And how glad I am that I didn’t! But that isn’t to say those who do are bad people. I just found a better way for myself to find a release.
If it’s comfortable being numb…how can there be comfort in pain?
This was the confusing part for me to work out. How could I enjoy the release which was very pleasurable sleeping with prostitutes, and yet still enjoy the pain of it all in eating breakfast cereals and milk for days because I had no money left?
I read an interesting article once in a psychology magazine. I had never picked one up before that day and have never picked another up since. But in this magazine on this day, whilst I sat in some Doctors surgery for half an hour, I truly learnt the key to the whole puzzle.
We who have addictive tendencies, don’t get a choice in what we become addicted to.
What? I hear you say. Yeah well its strange isn’t it? It’s not all that hard to grasp really. You know that song that you hear and you just can’t get it out of your head. Every time the radio plays it, you spend half a day singing it to yourself. Even years later when “Run to paradise” comes on, I still get caught up with the emotions I was feeling that day. I absolutely love that song.
Well that’s how a habit is formed. Repetition. The more I hear it, the more stronger my emotional response, the more I am addicted to it, or attracted to it. Even if it’s a not so pleasurable experience. Even if that experience is being beaten by your father in a fit of rage. The more he does it, the more I emotionally respond, the more I begin to crave that negative emotion. You become addicted to the pain. And in some ways when life is going along fine, if you are missing that pain in your life, you actively seek it out.
It's sad really. That’s why a woman stays with a man who beats her up. That’s why a junkie sells his soul for the junk he puts up his arm and that’s why a person will ritually cut themselves to feel the rush of pain. We are addicted to the pain, just as much as to the pleasure. And just like light follows darkness, after the pleasure we seek the pain, and when we are in pain we seek the pleasure, and we continue to exist.
We all enjoy feeling comfortable. We all enjoy being safe and secure where we are. Take us away from what we know, take us to another state or city suddenly and tell us to deal with it and we have a problem. We need to change slowly, but given the choice we like to stay with what we know. Why else would a country approve of a president who blatantly lies to his people? We don’t like change and we only do it if forced upon us. It’s only when a wife is beaten so very badly that the authorities step in and keep her from her husband by locking him up, that the wife accepts separation. But she has no choice in this matter. So she quickly goes out to a pub and finds another guy to beat her up.
She can’t help it. She doesn’t like getting beaten up. And her friends can’t understand her for going back. But that’s the only sort of love she knows and that’s the only love her daddy taught her. He regularly beat her mother up and in between beating her he made love to her mother and brought her presents home from work. And if he was a fine example of an alcoholic father he even made special visits to his daughter’s room to comfort her and run his filthy hands over her and molest her.
Oh yes She remembers the love, and she remembers the pain, and somehow they melded into one, and that was called life. To her, or to the heroin addict or to you the reader, life is all about feeling comfortable with our lot and coping as best we can in the circumstances.
How do I know about pain….
Have you ever had a man shove his penis up your behind? I mean shove it right in there so you can feel the tears flowing down your cheeks. Have you ever had to lay down and push your bum in the air and let a beast put it into you with all his might? It’s not fun. Its not love, and if you’ve been there, it’s not something you forget real easy. Worse still is the guilt you feel for putting yourself in the position that allowed it. Oh what a fool you were. If only you weren’t so craving pain in your life, things like this wouldn’t happen. And soon you believe it is all your fault. And then you begin to take comfort in the pain.
One day you are seeking the pain. One day you become comfortably numb. You go through the motions, you allow the lightning pain, and you switch off to it by a sheer act of will power. It seems as you lie there and let a man rip your insides with his penis that Pink Floyd may have been singing about this pain when they were singing. Maybe it wasn’t heroin, but the pain, and you’re switching off to it all, that makes you numb. Maybe you weren’t as smart as you thought you were when you are young, and the wisdom of a life half lived has served to give your life a richer and more rewarding tapestry.
It’s a sad cycle. The addicted are addicted to the week of poverty and no food after one night down at the pokies or one night with the prostitutes. We feel lonely, hopeless and we have no hope in life, so we confirm what a sad person we are when we live in poverty and prove with cheap clothes a free charity meals that we really are a loser like everyone things we are. It’s not fun eating cereal for a week. It’s not fun nursing a black eyes once very few weeks, it’s not fun having to go up the street everyday saying can people spare you change for a bus fare, it’s not fun, but we are so useless and we are so lacking in self worth we just love the feeling of shame, guilt and stupidity and we beat ourselves up with it. We make all our promises. If he beats me up one more time I will leave. If that girl does not kiss me this time I am never going to see her again. If this jockey does not ride that horse in next week that is it for me and punting. We are weak, we are hopeless and we are addicted to feeling that way.
The hardest thing about not sleeping with a prostitute for three months is not feeling the week of guilt after we have partaken of that sin. Especially when you are a Christian. It’s fine not to get the high, but how am I going to get that rush of guilt each week that I am in love with and addicted to?
And then there is the high. It’s in the paper ringing private escorts working in their own rented apartments and interviewing them one by one a few days before you get the money. You narrow it down and pick one and then five hours after you have been paid you are in bed with her. No matter how much you cry to God about your wicked sin, here you are trying to bring pleasure to a professional so that you can feel like a man and have a good time, and if she’s a professional she’ll have you convinced you did bring her to orgasm. If this is all to crude for you, you can jump to the next paragraph. In twenty years of this addiction, I have only been convinced of about three orgasms of the prostitutes I have been with. And boy, twenty years worth of once a week, or once every two weeks of seeing a sex worker, you do the maths, that’s why I don’t own a house.
You see I am poorly dressed and poor in assets and have never had any reason to really write a will because most of my life my addiction kept me broke.
Boy I can relate to people in addictions. The only way I came out of my addiction the time the original of this piece was written in 2005 and now in 2006 my two successful times of reprieve from the addiction was when I repented with many tears before God with all my heart and not wishing with all my heart to ever go back to these ladies. I had to love the girls and stay away and not abuse them, I had to love God enough not to break His heart with my sin with sleeping with a girl I was not married to, and I had to love myself enough not to degrade my self esteem by becoming a sex starved brute.
The only way out of my addiction was to hate it.
The problem with many of us is this addiction to the highs and the lows.
Oh I know about the rush of horse racing I did that for many years. There’s nothing like buying a car from your winnings one week. There’s nothing like seeing your horse win the race and it’s because you were a smart little punter watching all of that horses races since it first started racing and knowing that it can only win certain races at certain distances according to the track, the rider, the breeding and the time in the current campaign it is in. There’s a skill of knowing which race the owner and trainer are wanting to win with the horse and what races the horse is only racing to stay fit. There’s knowing which jockey will ride the horse when the horse has got to look like its trying to win the race and it’s the race favourite, but the owner, the trainer and the serious in the know punters connected to the stable want it not even to run a place and definitely at all costs do not want it to win the race. There really are so many factors to consider as a horse punter, it’s no wonder big high profile people in the business world are kings and respected for placing million dollar bets.
Racing stroked my ego on the high side when I won, and when I had a big loss on a big punt it made me feel like the loser I was when I lost. So how could I lose? lol
And what about today five years on?
I am comfortable and I am not addicted any more. I attend a church where I am loved and I have began to preach in a few churches. My Lord Jesus trusts me today to help strangers find their way to Him and to healing and I am in love with myself. I am quite impressed with what articles I have written five years ago and a lot has happened in my life since then. I have been Baptised and now have some giftings that Jesus has given me so that I can better witness to people. He has given the ability to "Know" a person's pain and their struggle and know things about them that they haven't told me. He gives me the ability to give strangers a message from Him and that just makes me so happy to be out and about doing that.
I have not seen my son in six years and that is sad but it was his mother's wish and I didn't fight it. I have had another breakdown and now am wiser and have stayed on my medication for four years without a serious incident. It seems the more hard balls life throws at me the more confident I am in the power and the love of Jesus to pull you through anything.
I really enjoy sharing a message with a person through prophecy when Jesus speaks through me as I really enjoy seeing Him speak. He is such a magnificent, wonderful, caring and patient God that was man. It is so good to have a God in heaven called Jesus who thinks and reasons like a man but with all the power of God behind Him.
Jesus is just so real to me. I have seen Him in visions close to ten times now and some of them have been so very memorable. He told me once that I was his hidden treasure and if you are reading this I am sure He would tell you the same also. He is so sweet, I do not need another person to sustain me. He is my everything and He is such a loyal and honest and caring friend.
With much love,
